Striking a balance between humor and humility is one of the toughest things to do in any form of storytelling, but just with this trailer, director Jonathan Levine and a cast that includes Joseph Gordon-Levitt, Seth Rogen, and Anna Kendrick look like they’ve done just that. Plus, they’ve done it while mocking the big baddie of the disease world. Formerly titled I’m with Cancer, 50/50 is a title that keeps the odds of the main character living front and center (even if they basically spoil that point in the opening part of the trailer), and the rest is filled with heads being shaved with questionable trimmers, therapy sessions, and foolish attempts at cancer-based pick-up lines.

Kevin Carr breaks down the week’s releases, looking at Funny People, Aliens in the Attic, and The Collector.